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Handbooks in Pharmacology and Toxicology


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Molecular Bases of Anesthesia

Molecular Bases of Anesthesia

1st Edition

Edited By Eric Moody, Phil Skolnick
December 28, 2000

Molecular Bases of Anesthesia provides a clear overview of the state of knowledge about anesthetic mechanisms at the molecular level of occurrence and focusing on the latest state-of-the-art techniques that relate to how anesthetic drugs cause unconsciousness. With contributions by leading experts,...

Cell Death The Role of PARP

Cell Death: The Role of PARP

1st Edition

Edited By Csaba Szabo
June 22, 2000

Poly (ADP-ribose) polymerase (PARP), also termed poly (ADP-ribose) synthetase (PARS) is a nuclear enzyme with a wide range of functions, including regulation of DNA repair, cell differentiation, and gene expression. More than a decade after the identification of PARP-like enzymatic activities in ...

Handbook of Alcoholism

Handbook of Alcoholism

1st Edition

Edited By Gerald Zernig, Alois Saria, Martin Kurz, Stephanie O'Malley
March 24, 2000

While the war on drugs continues to attract world attention, it is often overlooked that alcoholism remains a major worldwide health concern. No matter what your expertise, the CRC Handbook of Alcoholism can help you acquire the necessary skills to treat problem drinkers and alcohol-dependent ...

Manual of Immunological Methods

Manual of Immunological Methods

1st Edition

By Canadian Networking
July 02, 1998

The Manual of Immunological Methods represents the collaboration of the Canadian Network of Toxicology Centers, a non-profit network of university-based scientists dedicated to research, training, risk assessment, and communication. This manual provides detailed immunological methods that can be ...

Anabolic Treatments for Osteoporosis

Anabolic Treatments for Osteoporosis

1st Edition

Edited By James F. Whitfield, Paul Morley
October 20, 1997

Osteoporosis, a growing epidemic among women in North America, Europe, and Japan, is a painful, costly disease that has presented a treatment challenge to healthcare professionals. Until recently, therapies have focused on agents that slow bone resorption, and have had only limited success at ...

Muscarinic Receptor Subtypes in Smooth Muscle

Muscarinic Receptor Subtypes in Smooth Muscle

1st Edition

Edited By Richard M. Eglen
January 21, 1997

This book explores several subtypes of muscarinic receptors that modulate smooth muscle activity. Main topics include a classification of muscarinic receptors, biochemical responses that occur in smooth muscle, the role of muscarinic receptors in the function of gastrointestinal and genitourinary ...

Airway Wall Remodelling in Asthma

Airway Wall Remodelling in Asthma

1st Edition

By A. G. Stewart
September 24, 1996

Asthma is a disease of high prevalence that has shown a trend toward increasing incidence, morbidity, and mortality over the last three decades despite apparently effective drug treatments and increasing awareness of the need for better disease management. Often the inflammatory component of asthma...

Chemoattractant Ligands and Their Receptors

Chemoattractant Ligands and Their Receptors

1st Edition

By Richard Horuk
August 14, 1996

Chemoattractant Ligands and Their Receptors succinctly summarizes cutting-edge research in the important area of chemoattraction in immunology. It explains how chemoattractant molecules mobilize immune cells to ward off attack by invading pathogens, both at a molecular and at a cellular level. ...

Experimental Models of Mucosal Inflammation

Experimental Models of Mucosal Inflammation

1st Edition

By Timothy S. Gaginella
November 03, 1995

Written by active researchers in the field, this unique book provides a detailed review of esophageal, gastroduodenal ileal, and colonic models of mucosal inflammation and ulceration. Animal Models of Mucosal Inflammation not only presents up-to-date techniques and models but also provides the ...

Serotonin and Gastrointestinal Function

Serotonin and Gastrointestinal Function

1st Edition

By Timothy S. Gaginella, James J. Galligan
July 25, 1995

Serotonin and Gastrointestinal Function provides a comprehensive review of current research into the mechanisms by which serotonin acts on gastrointestinal tissues. This book covers neurochemistry, physiology, pharmacology, and clinical issues relevant to serotonin in the gastrointestinal tract. ...

Taxol Science and Applications

Taxol: Science and Applications

1st Edition

Edited By Matthew Suffness
May 25, 1995

This volume brings together all aspects of TAXOL® research, development, and clinical use. It provides comprehensive knowledge of the compound and a perspective of the complex interrelationships needed for its development and production. Each chapter is written by an authority in the field. ...

Endothelin Receptors From the Gene to the Human

Endothelin Receptors: From the Gene to the Human

1st Edition

By Robert R. Ruffolo, Jr.
May 19, 1995

Since the discovery of endothelin, major advances have been made in understanding the molecular structure and function of the endothelin receptors. At least two subtypes of receptors, designated ETA and ETB, have been identified through biochemical and pharmacological techniques. These subtypes are...

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